Kim JM, Yang YS, Xie J, Lee O, Kim JH, Hong J, Boldyreff B, Filhol-Cochet O, Chun H, Greenblatt MB, Gao G, and Shim JH. Regulation of sclerostin by the SIRT1 stabilization pathway in osteocytes. Cell Death Differ. Feb 15, 2022
Greenblatt MB*, Shim JH*, Bok S, and Kim JM. The ERK MAPK pathway in osteoblasts. J. Bone Metabol. 29(1):1-15, 2022 (*co-corresponding authorship)
Eekhoff EMW., de Ruiter RD., Smilde BJ, de Vries T., Schoenmaker T., Netelenbos CN., Hsiao E., Pals G., Shim JH, Gao G., Kaplan F. Pignolo R., and Micha M. Gene therapy in Fibrodysplasia Ossificans Progressiva (FOP): Feasibility and obstacles. Human Gene Ther. 33(15-16):782-788, 2022
John AA, Xie J, Yang YS, Kim JM, Lin C, Ma H, Gao G, and Shim JH. AAV-mediated delivery of osteoblast/osteoclast-regulating miRNAs for osteoporosis therapy. Mol Ther Nuc Acids. 29:296-311, 2022
Kim JM, Yang YS, Hong JH, Chaugule S, Chun H, van der Meulen M, Greenblatt MB, and Shim JH. Biphasic regulation of osteoblast development via the ERK MAPK-mTOR pathway. eLife, 11:e78069, 2022
Yang YS, Kim JM, Xie J, Chaugule S, Lin C, Ma H, Hsiao E, Hong JH, Chun H, Shore EM, Kaplan FS, Gao G, and Shim JH. Suppression of Heterotopic Ossification in Fibrodysplasia Ossificans Progressiva Using AAV Gene Therapy. Nat. Commun. 13(1):6175.
Oh WT, Yang YS, Xie J, Ma H, Kim JM, Park KH, Oh DS, Park-Min KH, Greenblatt MB, Gao G, and Shim JH. WNT-modulating gene silencers as a gene therapy for osteoporosis, bone fracture, and critical-sized bone defects. Mol. Ther. S1525-0016(22), 2022.
Lin C, Yang Q, Gao D, Xie J, Yang YS, Chaugule S, DeSouZa N, Oh WT, Li R, Chen Z, John AA, Qui A, Zhu LJ, Greenblatt MB, Ghosh S, Li S, Gao G, Haynes C, Emerson CP, and Shim JH. Impaired mitochondrial oxidative metabolism in skeletal progenitor cells leads to musculoskeletal disintegration. Nat. Commun. 13(1):6869.